Iatrogenic Allogenosis vs. Secondary Allogenosis in Cali, Colombia. A Case Report
DOI:
https://doi.org/10.16925/cf.v3i2.1778Keywords:
adjuvants, iatrogenic allogenosis, biopolymers, plastic surgery, autoimmune/ inflammatory syndrome induced by adjuvants (asia)Abstract
Introduction: Overall, cosmetic surgery has been growing in popularity; likewise, the number of clandestine places that perform these surgeries has increased and, thus, the incidence of complications, morbidity, and direct mortality. Materials and methods: Based on twelve cases assessed between 2009 and 2014 by the Forensic Clinical Group at the Southwestern Regional Office of the National Institute of Legal Medicine and Forensic Sciences, involving patients who underwent some cosmetic surgery related to the use of filling materials, we described the development of disease by biopolymers or iatrogenic allogenosis.
Summary of cases: Twelve women underwent aesthetic procedures and developed symptoms and signs of disease by filling substances: pain at injection sites, tumors, and even abscesses in the affected areas Results and discussion: In our report, 100% of the cases were young adult women who had signs and symptoms in common after aesthetic interventions such as buttock augmentation (most common procedure), and even showed manifestations of autoimmunity (autoimmune syndrome/inflammatory syndrome induced by adjuvants). Conclusions: Medical-legal sequels were found in seven of the women, the majority of whom exhibited physical deformity affecting the body and permanent functional disruption of the integumentary organ system. This reflects the danger of allogenic substances (whether approved by the Invima or not) when injected by non-qualified personnel.
Author Biography
Ana Inés Ricaurte Villota, Instituto Nacional de Medicina Legal y Ciencias Forenses
Médico Forense
References
Kagan HD. Sakurai injectable silicone formula. Pre-liminary report. Arch Otolaryngol. 1963;78:663-8.
Ortiz-Monasterio F, Trigos I. Management of pa-tients with complications from injections of for
-eign materials into the breasts. Plast Reconstr Surg. 1972;50(1):42-7.
Sánchez-Carpintero I, Candelas D, Ruiz-Rodríguez R. Materiales de relleno: tipos, indicaciones y com-
plicaciones. Actas Dermosifiliogr. 2010;101:381-93. doi: 10.1016/j.ad.2010.01.004
Bartsich S, Wu JK. Silicon emboli syndrome: A sequela of clandestine liquid silicone injections. A
case report and review of the literature. J Plast Re-constr Aesthet Surg. 2010;63(1):e1-3. doi: 10.1016/j.
bjps.2009.04.004
Coiffman F. Alogenosis iatrogénica: una nueva enfermedad. Cir Plást Iberolatinoam. 2008;34(1):1-10.
doi: 10.4321/S0376-78922008000100002
Sanz-Barriga HA, Eróstegui-Revilla CP. Alogenosis iatrogénica, el gran peligro de los biopolímeros. Rev
Cient Cienc Méd. 2010;13(1):31-4.
Priego R. La enfermedad por modelantes Un problema de salud pública. Cirugía Plástica.
;20(3):104.
Perricone C, Colafrancesco S, Mazor RD, et al. Auto-immune/inflammatory syndrome induced by adju-
vants (asia) 2013: Unveiling the pathogenic, clinical and diagnostic aspects. J Autoimmun. 2013;47:1-16.
doi: 10.1016/j.jaut.2013.10.004
Rees TD, Platt J, Ballantyne DL Jr. An investigation of cutaneous response to dimethylpolysiloxane (sil-
icone liquid) in animals and humans-a preliminary report. Plast Reconstr Surg. 1965;35:131-9.
Narins RS, Beer K. Liquid injectable silicone: A review of its history, immunology, technical considerations, complications, and potential. Plast Reconstr Surg. 2006;118(3 Suppl):77S-84S. doi: 10.1097/01.prs.0000234919.25096.67
Domínguez-Zambrano A, Haddad-Tame JL, Torres-Baltazar I, Jiménez-Muñoz G, Sastré-Ortiz N,
Espinosa-Maceda S. Enfermedad por modelantes: problemática actual en México y presentación de
casos. Cir Plást Iberolatinoam. 2013;39(4):399-405.
Gordillo-Hernández J, Alegre-Tamez E, Torres-Baltazar I, Mendieta-Espinosa MJ, Sastré-Ortiz N.
Abordaje multidisciplinario de la enfermedad humana por infiltración de sustancias modelantes. Cir
Plást Iberolatinoam. 2013;39(3):269-77.
García-Soto G, Castaño J, Smith-Meneses R. Linfadenopatía por silicona en una paciente con
prótesis mamarias. Rev Colomb Obstet Ginecol. 2006;57(2):112-5.
Ojeda P, DeVivero A, Moreno A, Sossa M. Embolismo por silicona. Reporte de casos y revisión de la
literatura. Rev Colomb Neumol. 2004;16(3):193-7.
Stanford N, Montealegre G. Alogenosis iatrogénica, hallazgos de una enfermedad reumática. Rev Co-
lomb Cirugía Plástica y Reconstr. 2013;19:28-38.
Vera-Lastra O, Medina G, Cruz-Domínguez M del P, Jara MJ, Shoenfled Y. Autoimmune/inflamma-
tory syndrome induced by adjuvants (Shoenfeld’s syndrome): Clinical and immunological spectrum.
Expert Rev Clin Immunol. 2013;9(4):361-73. doi: 10.1586/eci.13.2
Gutiérrez-González LA, Pérez-Alfonzo R, Párraga de Zoghbi B. Iatrogenic allogenic case report. Re-
search. 2014;1:753. doi: dx.doi.org/10.13070/rs.en. 1.753
Parsons RW, Thering HR. Management of the silicone-injected breast. Plast Reconstr Surg. 1977;
(4):534-8.
Castillo MDP. El bello negocio de la cirugía plástica. Posiciones. 2011;(2):59-66.
Agencia efe. Los desempleados recurren a cirugía estética para aumentar opciones laborales. El Comercio
[en línea]. 12 de marzo de 2012. Disponible en Internet: http://www.elcomercio.es/agencias/20120311/
mas-actualidad/sociedad/desempleados-recurren-cirugia-estetica-para_201203111321.html
Torres B, Burgos R, Medrano G, Priego RB. Instrumento para evaluar y estadificar el daño producido
por la infiltración de sustancias modelantes. Cirugía Plástica. 2010;20(3):105-11.
